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Anaplasma platys PCR testing identifies the causative agent of Canine Infectious Cyclic Thrombocytopenia, a tick-borne disease that specifically targets platelets in dogs. This pathogen causes characteristic cyclic thrombocytopenia with recurring episodes of platelet reduction, which can lead to bleeding disorders and is often subclinical or co-infected with other tick-borne pathogens, making molecular detection critical for accurate diagnosis.
Platelet-Specific Pathogen DetectionCyclical Infection Pattern AssessmentCo-infection IdentificationSubclinical Case DetectionBleeding Risk Evaluation.png)
Anaplasma platys (formerly Ehrlichia platys) is a gram-negative bacterium transmitted primarily by Rhipicephalus sanguineus ticks. It specifically infects platelets, causing their destruction and resulting in cyclic thrombocytopenia characterized by periodic platelet count decreases every 1-2 weeks. Most infections are mild or subclinical, but co-infections with other tick-borne pathogens like Ehrlichia canis can lead to more severe clinical presentations. Geographic distribution is worldwide, with prevalence in tropical and subtropical regions.
Clinical Significance of A. platys Testing
Platelet Tropism: Unique affinity for platelets causing cyclic thrombocytopenia.
Co-infection Synergy: Often occurs with other tick-borne pathogens, worsening clinical signs.
Subclinical Presentation: May cause silent infection with periodic platelet drops.
Differential Diagnosis: Important consideration in cases of unexplained thrombocytopenia.
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